منابع مشابه
Biomarkers in Prostate Cancer Epidemiology
Understanding the etiology of a disease such as prostate cancer may help in identifying populations at high risk, timely intervention of the disease, and proper treatment. Biomarkers, along with exposure history and clinical data, are useful tools to achieve these goals. Individual risk and population incidence of prostate cancer result from the intervention of genetic susceptibility and exposu...
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A n international team of researchers believe they may have found, if not the smoking gun, at least a few DNA “bullets” that determine whether prostate cancer will become aggressive. A new biomarker study, which appeared in the Aug. 16, 2011, online edition of Cancer Epidemiology, Biomarkers, and Prevention, identified five inherited genetic variants associated with aggressive prostate cancer. ...
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Prostvac is a poxviral-based vaccine designed to target prostate-specific antigen (PSA) in prostate cancer patients. Recently, the potential toxicity and immunological impact of this immunotherapy were reviewed in the context of new clinical data. Our findings suggest that Prostvac is safe and elicits anticancer immune responses, both alone and in combinatorial approaches.
متن کاملNext generation biomarkers in prostate cancer.
A wide spectrum of non-protein based biomarkers are under development that promises to revolutionize the care of prostate cancer (CaP) patients. In the context of CaP detection we highlight the potential value of the urine tests PCA3 and Prostarix(TM), especially for their ability to stratify patient risk with previous negative biopsy for occult cancer. The search for such markers is made more ...
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EK There are 4 biopsy-based biomarker tests on the market for men who have not undergone surgery: Oncotype DX prostate cancer test from Genomic Health, Decipher Biopsy from GenomeDx, Prolaris from Myriad Genetics, and ProMark from Metamark Genetics (Table). The way they work is that a biopsy sample is sent to the company laboratory, which analyzes the expression of various genes in the prostate...
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ژورنال
عنوان ژورنال: Human Vaccines & Immunotherapeutics
سال: 2014
ISSN: 2164-5515,2164-554X
DOI: 10.4161/hv.28032